Nanotechnology in biomedicine
Abstract
A brief overview of the impact of nanotechnology on biomedicine and life science will be
given as well as examples where nanotechnology has benefited by borrowing concepts from
nature.
The rest of the talk will focus on our recent work on the integration of molecular motors of
mucle , (myosin and actin) with nanotechnology. Three aspects of our work will be
considered: 1 The use of molecular motors for cargo-transportation in nanotechnology (labon-a-chip, factory on a chip); 2. The use of nanotechnology for fundamental studies of how
the molecular motors work and 3. The development of highly miniaturized high-througput
drug screening systems with molecular motors as intended drug targets.
Statistik
Referenser
Månsson, A, Sundberg, M., Bunk, R., Balaz, M., Nicholls, L, Omling, P., Tegenfeldt, l, Tågerud, S., Montelius, L., 2005. Actin-based molecular motors for cargo transportation in nanotechnology - potentials and challenges IEEE trans Adv Pack, in press. https://doi.org/10.1109/TADVP.2005.858309
Bunk, R., Klinth, l, Montelius, L., Nicholls, I., Omling, P., Tågerud, S., Månsson, A., 2003. Actomyosin motility on nanostructured surfaces Biochem Biophys Res Commun 301,783.
Bunk, R., Sundberg, M., Nicholls, I., Omling, P., Tågerud, S., Månsson, A., Montelius, L., 2005. Guiding motor-propelled molecules with nanoscale precision through silanized bi-channel structures Nanotechnol 16,710.
Bunk, R., Månsson, A., Nicholls, I., Omling, P., Sundberg, M., Tågerud, S., Carlberg, P., Montelius, L., 2005. Guiding molecular motors by nanoimprinted structures Jap J Appl Phys 44, 3337.
Månsson, A, Sundberg, M., Balaz, M., Bunk, R., Nicholls, I., Omling, P., Tågerud, S., Montelius, L., 2004. In vitro sliding of actin filaments labelled with single quantum dots Biochem Biophys Res Commun 314, 529. https://doi.org/10.1016/j.bbrc.2003.12.133
