Pigment dispersion syndrome with possible visual field loss (in Norwegian)

Authors

  • Ellen Svarverud Buskerud University College, Department of Optometry and Visual Science, Frogs vei 41, 3611 Kongsberg, Norway

DOI:

https://doi.org/10.5384/sjovs.vol3i1p8

Keywords:

Pigment dispersion ssyndrom, myopia, glaucoma, visual field loss

Abstract

Pigment dispersion syndrome (PDS) is a condition of the anterior segment of the eye characterised by pigment deposition on a number of ocular structures. The condition is usually bilateral but most commonly asymmetric. In PDS, pigment is released from the posterior surface of the iris due to friction between the zonules and the iris. In itself, the condition does not represent any problems for the patient, but pigment deposition in the trabecular meshwork may interfere with drainage of the anterior chamber fluid and cause pigmentary glaucoma (PG). This case report presents a young myopic female with many of the classic signs of PDS; Krukenberg’s spindle, transillumination of mid-peripheral iris, deep anterior chambers, concave iris profile and increased pigmentation in the trabecular meshwork. Various diagnostic methods were applied to reveal clinical signs and to establish the patient’s visual function. Optic nerve heads and intraocular pressure were normal, but visual fields were suspect. The patient was advised to make an appointment with an ophthalmologist. Risk factors for development of PG and management of patients with PDS will be discussed.

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References

Alward, W. L. M., & Longmuir, R. A. (2008). Color Atlas of Gonioscopy (2nd ed.). San Fransisco, USA: American Academy of Ophthalmology.

Andersen, J. S., Pralea, A. M., DelBono, E. A., Haines, J. L., Gorin, M. B., Schuman, J. S., ...Wiggs, J. L. (1997). A gene responsible for the pigment dispersion syndrome maps to chromosome 7q35-q36. Archives of Ophthalmology, 115, 384-388.

Bovell, A. M., Damji, K. F., Dohadwala, A. A., Hodge, W. G., & Allingham, R. R. (2001). Familial occurrence of pigment dispersion syndrome. Canadian Journal of Ophthalmology, 36, 11-17.

Campbell, D. G. (1979). Pigmentary dispersion and glaucoma. A new theory. Archives of Ophthalmology, 97, 1667-1672.

Chihara, E. (2008). Assessment of true intraocular pressure: the gap between theory and practical data. Survey of Ophthalmology, 53, 203-218. doi:10.1016/j.survophthal.2008.02.005

Collicott, T. (1998). Pigment-dispersion syndrome, and pigmentary glaucoma. Optician, 216(5674), 16-22.

Dorairaj, S. K., Robin, A., Shihadeh, W., Greenberg, S., Liebmann, J. M., & Ritch, R. (2007). Phenotypic variability of pigment dispersion syndrome in children. Archives of Ophthalmology, 125, 136-138.

Flammer, J., Drance, S. M., Fankhauser, F., & Augustiny, L. (1984). Differential light threshold in automated static perimetry. Factors influencing short-term fluctuation. Archives of Ophthalmology, 102, 876-879.

Flammer, J., Drance, S. M., & Zulauf, M. (1984). Differential light threshold. Short- and long-term fluctuation in patients with glaucoma, normal controls, and patients with suspected glaucoma. Archives of Ophthalmology, 102, 704-706.

Franklin, A. (2002). Pigment dispersion syndrome. Optician, 226(5931), 19-23.

Goldmann, H., & Schmidt, T. (1957). Applanation tonometry (Engelsk oversettelse). Reprint fra Ãœber applanationstonometrie. Ophthalmologica; 134: 221-242. In R. Ritch & R. M. Caronia (Eds.), (2000). Classic Papers in Glaucoma (pp. 155-162). The Hague, Netherlands: Kugler Publications.

Greenstein, V. C., Seiple, W., Liebmann, J., & Ritch, R. (2001). Retinal pigment epithelial dysfunction in patients with pigment dispersion syndrome: implications for the theory of pathogenesis. Archives of Ophthalmology, 119, 1291-1295.

Harwerth, R. S. (2004). Histopathology underlying glaucomatous damage - I. In R. N. Weinreb & E. L. Greve (Eds.), Glaucoma Diagnosis. Structure and Function (pp. 13-19). The Hague, Netherlands: Kugler Publications.

Heijl, A., Bengtsson, B., Patella, M., & Wild, J. (2004). Standard automated perimetry (SAP). In R. N. Weinreb & E. L. Greve (Eds.), Glaucoma Diagnosis. Structure and Function (pp. 83-92). The Hague, Netherlands: Kugler Publications. Henson, D. (2000). Visual fields (2nd ed.). Boston, USA: Butterworth-Heinemann.

Iester, M., Mete, M., Figus, M., & Frezzotti, P. (2009). Incorporating corneal pachymetry into the management of glaucoma. Journal of Cataract and Refractive Surgery, 35, 1623-1628. doi: doi:10.1016/j.jcrs.2009.05.015

Johnson, C. A., Fingeret, M., & Iwase, A. (2004). Frequency doubling technology (FDT) perimetry. In R. N. Weinreb & E. L. Greve (Eds.), Glaucoma Diagnosis. Structure and Function (pp. 109-117). The Hague, Netherlands: Kugler Publications.

Kampik, A., Green, W. R., Quigley, H. A., & Pierce, L. H. (1981). Scanning and transmission electron microscopic studies of two cases of pigment dispersion syndrome. American Journal of Ophthalmology, 91, 573-587.

Kanadani, F. N., Dorairaj, S., Langlieb, A. M., Shihadeh, W. A., Tello, C., Liebmann, J. M., & Ritch, R. (2006). Ultrasound biomicroscopy in asymmetric pigment dispersion syndrome and pigmentary glaucoma. Archives of Ophthalmology, 124, 1573-1576.

Kerrigan-Baumrind, L. A., Quigley, H. A., Pease, M. E., Kerrigan, D. F., &

Mitchell, R. S. (2000). Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons. Investigative Ophthalmology and Visual Science, 41, 741-748.

King, A. J., Taguri, A., Wadood, A. C., & Azuara-Blanco, A. (2002). Comparison of two fast strategies, SITA Fast and TOP, for the assessment of visual fields in glaucoma patients. Graefe’s Archive for Clinical and Experimental Ophthalmology, 240, 481-487. doi: 10.1007/s00417-002-0482-y

Küchle, M., Mardin, C. Y., Nguyen, N. X., Martus, P., & Naumann, G. O. (1998). Quantification of aqueous melanin granules in primary pigment dispersion syndrome. American Journal of Ophthalmology, 126, 425-431. doi: 10.1016/S0002-9394(98)00098-1

Lin, D. Y., Volpicelli, M., & Singh, K. (2003). Dense pigmentation of the posterior lens capsule associated with the pigment dispersion syndrome. Journal of Glaucoma, 12, 491-493.

Nicolela, M., Anton, A., Asawaphureekorn, S., Burgoyne, C., & Tomita, G. (2004). Scanning laser tomography (HRT). In R. N. Weinreb & E. L. Greve (Eds.), Glaucoma diagnosis. Structure and Function (pp. 53-60). The Hague, Netherlands: Kugler Publications.

Niyadurupola, N., & Broadway, D. C. (2008). Pigment dispersion syndrome and pigmentary glaucoma--a major review. Clinical and Experimental Ophthalmology, 36, 868-882. doi: 10.1111/j.1442-9071.2009.01920.x

Qing, G., Wang, N., Tang, X., Zhang, S., & Chen, H. (2009). Clinical characteristics of pigment dispersion syndrome in Chinese patients. Eye (Lond), 23, 1641-1646. doi: 10.1038/eye.2008.328

Ritch, R. (1998). Pigment dispersion syndrome. American Journal of Ophthalmology, 126, 442-445.

Roberts, D. K., Chaglasian, M. A., & Meetz, R. E. (1997). Clinical signs of the pigment dispersion syndrome in blacks. Optometry and Vision Science, 74, 993-1006.

Siddiqui, Y., Ten Hulzen, R. D., Cameron, J. D., Hodge, D. O., & Johnson, D. H. (2003). What is the risk of developing pigmentary glaucoma from pigment dispersion syndrome? American Journal of Ophthalmology, 135, 794-799. doi: 10.1016/S0002-9394(02)02289-4

Sokol, J., Stegman, Z., Liebmann, J. M., & Ritch, R. (1996). Location of the iris insertion in pigment dispersion syndrome. Ophthalmology, 103, 289-293.

Sugar, H. S., & Barbour, F. A. (1949). Pigmentary glaucoma; a rare clinical entity. American Journal of Ophthalmology, 32, 90-92.

Svarverud, E. (2007). Gonioskopi. Optikeren, 4, 40-44.

Turgut, B., Turkcuoglu, P., Deniz, N., & Catak, O. (2008). Annular and central heavy pigment deposition on the posterior lens capsule in the pigment dispersion syndrome: pigment deposition on the posterior lens capsule in the pigment dispersion syndrome. International Ophthalmology, 28, 441-445. doi: 10.1007/s10792-007-9158-2

van der Schoot, J., Reus, N. J., Colen, T. P., & Lemij, H. G. (2010). The ability of short-wavelength automated perimetry to predict conversion to glaucoma. Ophthalmology, 117, 30-34. doi: 10.1016/j.ophtha.2009.06.046

Wadood, A. C., Azuara-Blanco, A., Aspinall, P., Taguri, A., & King, A. J. (2002). Sensitivity and specificity of frequency-doubling technology, tendency-oriented perimetry, and Humphrey Swedish interactive threshold algorithm-fast perimetry in a glaucoma practice. American Journal of Ophthalmology, 133, 327-332. doi: 10.1016/S0002-9394(01)01424-6

Yücel, Y. (2004). Histopathology underlying glaucomatous damage - III. In R. N. Weinreb & E. L. Greve (Eds.), Glaucoma Diagnosis. Structure and Function (pp. 33-37). The Hague, Netherlands: Kugler Publications.

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Published

2010-12-01

How to Cite

Svarverud, E. (2010). Pigment dispersion syndrome with possible visual field loss (in Norwegian). Scandinavian Journal of Optometry and Visual Science, 3(1), s. 8–14. https://doi.org/10.5384/sjovs.vol3i1p8

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Case Report

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